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About Dr. Theo

Dr. Theo?s ground-breaking book, ?The Arthritis Cure? introduced millions to the benefits of glucosamine and chondroitin years before the National Institute of Health confirmed the value of these important supplements just this year. Dr. Theo?s own brand, AVOSOY? Complete, includes the finest ingredients and the correct forms and dosage levels of glucosamine and chondroitin other supplements often cannot match.

And now, Dr. Theo proudly introduces ASU, Avocado-Soybean-Unsaponifiable, a supplement that has shown to help millions improve their joint health without the side effects of prescription and over-the-counter pain relievers.

Read more about ASU below or simply Order AVOSOY? Complete today and once again join others who are experiencing a better life by protecting their joint health years ahead of traditional medicine because of Dr. Theo?s continuing research.

ASU Information - Index

Introduction - What is ASU
How is ASU made?
How does ASU work?
Who should consider using ASU?
What are the side effects of using ASU?
ASU research
Does ASU interact with medications or other supplements?
Who should not use ASU?
Why not just eat more avocados and soy products rather than take ASU?
Many products will say “ASU” on them, which ones can I trust?
Report Your Experience With ASU Here
ASU Products

Introduction - What is ASU?

Avocado-Soybean Unsaponifiable (or ASU) is an entirely new product that has helped millions improve their joint health without the side effects of prescription and over-the-counter pain relievers.

ASU is mixture of healthy substances derived from small portions of avocado and soybean oils that can dramatically improve joint health.

In the US, ASU is sold as a dietary supplement for improving joint health. No prescription is required.

ASU should become a major addition to the treatment of osteoarthritis, just as glucosamine and chondroitin have become over the past few years after the release of the first edition of the book The Arthritis Cure.

ASU has special features, however. It is a totally vegetarian product, suitable for vegans and anyone else wishing to avoid animal products. It works by a different mechanism from other substances, is a once per day dose, and even helps slow cartilage loss in severe cases of osteoarthritis.

Finally, ASU saves money. ASU users often partially or fully eliminate their expensive anti-inflammatory medications (e.g. Celebrex® costs almost $3 per day). The symptom improvements from ASU might also save money that would otherwise be spent on physical therapy or surgery.


How is ASU made?

Avocado-Soybean Unsaponifiable or ASU is derived entirely from vegetable sources. It is isolated from a certain fraction of the oil from avocados and soybeans.

In fact, less than one percent of the avocado and soy oils make up the unsaponifiable fraction (or portion) of these oils. The unsaponifiable fraction is then stripped from the fibers that bind it so it can be better absorbed when taken by mouth.

What is unsaponifiable? Saponifiable is a chemical term used to describe a substance that can be mixed with lye to form soap. Saponifiable oils, mixed with lye are the basis of almost all soap products we use.

Unsaponifiable oil fractions cannot form soap and, like other “good” fats, have special health benefits when ingested. The avocado portion of ASU has special properties of its own.


How Does ASU Work?

ASU has been shown to improve joint health by stimulating the production of new cartilage while reducing the breakdown of existing cartilage.

This applies to both major cartilage components: the collagen component that provides the framework and the large proteoglycan molecules that give cartilage its shock absorbing and friction-free properties.

Unlike other substances that can stimulate collagen production, ASU causes cartilage cells to produce the four types of collagen for the joint cartilage in the exact same proportion as is found in normal, healthy joint cartilage.

In addition, ASU decreases pain, inflammation and the need for pain relievers and anti-inflammatory drugs, in the majority of users. This alone is a major reason to use ASU. But the news is even better. The safety data on ASU is spectacular, far superior to the (often dangerous) pain relievers and NSAIDs.

Unlike other supplements or drug treatments for osteoarthritis, ASU apparently works even better in those who have more severe cartilage loss.

ASU appears to benefit cartilage even in those who do not have any noticeable change in their symptoms. This is similar to calcium supplements helping with bone mineral density without affecting a person’s symptoms (you can’t feel calcium helping your bones, for instance). As a result, people should consider staying on ASU supplements even if they require additional pain relievers.

If you would like to see the mechanism of action of how ASU works, see the section on ASU Research.


Who should consider using ASU?

ASU should be considered as a joint health supplement for the following people:

• Diagnosed with, or are at high risk for developing osteoarthritis

Risks include: joint pain or stiffness, strong family history of osteoarthritis, history of severe joint injury, orthopedic surgery, cartilage tear or cartilage removal

• Using anti-inflammatories, or NSAIDs (any on the list; trade names at right)

List of NSAIDs

• Using pain relievers for joint pain or stiffness

These include Tylenol® or other brands of acetaminophen

• Using rub-on treatments for joint pain or stiffness

• Taking glucosamine or chondroitin who want additional joint protection, pain relief or improvement in joint range of motion

• Who have not found improvement in symptoms after taking glucosamine and chondroitin for a period of several months

• Who desire a vegetarian joint health supplement

• Who are interested in preventive joint health

• Diagnosed with or at high risk for periodontal (gum) disease (ASU is also used for this condition)


What are the side effects of ASU?

There are no significant side effects compared to a placebo in the controlled clinical studies of ASU. Nevertheless, anytime people consume something by mouth, including an inactive placebo, various foods, or even empty capsules, they can experience mild stomach upset.


Research Summary


The basic science evidence shows that ASU:

• Increases chondrocyte collagen synthesis without altering proportions of collagen

• Stimulates the expression of Transforming Growth Factor (TGF-b1, TGF-b2) , and Plasminogen Activator Inhibitor (PAI-1) which indicates stimulation and repair of cartilage matrix

• Inhibited chondrocytes’ spontaneous production and IL-1 induced production of IL-6, IL-8, PGE2 and stromelysin, chemicals that are associated with the breakdown of joint cartilage.

• Inhibited chondrocytes’ of IL-6, IL-8, PGE2 and stromelysin and collagenase

• Partially inhibits negative effect of IL-1b on collagen synthesis

To view all of the research on ASU click here


ASU Q&A - Other

Does ASU interact with medications or other supplements?

We are not aware of any interactions at this time. We will be collecting data to see if any tends develop, and report this on this site, but the long history of use of ASU as a prescription treatment is comforting. If you notice anything suspicious or if you just want to tell us how well you're doing with ASU, Report Your Experience With ASU Here.


Who should not use ASU?

ASU has not been studied in children (age 17 or less), pregnant or nursing women. There’s no indication of harm from ASU, but no evidence of safety, either. Don’t experiment if you’re not sure and always consult with your physician before starting any new drug or supplement, including ASU.


Why not just eat more avocados and soy products rather than take ASU?

Since only a small portion of avocados and soybeans are the oil, and less than 1/100th of the oil is the unsaponifiable portion, and that this portion has to be separated from certain fibers to be absorbed, it is unlikely you’d see significant benefits from eating (even large amounts) of avocados and soy products.

Furthermore, avocados have to be picked and processed at just the right time. Too young or too old and the concentration of the desired material is too low.


Many products will say “ASU” on them, which ones can I trust?

This is going to be a big issue, especially at first. Poorer quality products will appear quickly, this seems to happen when any new category is introduced, especially when expensive raw materials are involved.

We will help sort out which products are worthwhile and report them on

One general rule, beware of anything that says “Avocado and/or Soy Oil.” This is not the same thing as ASU and does not have the same function. Only about 1% of these oils are the unsaponifiable fraction and even then, this fraction has to be stripped of its non-digestible fiber before you can even absorb the active ASU.

When a product is produced, each batch should be tested for potency before being shipped. Very few products have had such testing, and few are even manufactured in facilities fully compliant with industry-established good manufacturing practices (or GMPs).

Ideally, an ASU product should be produced in a facility that not only makes supplements, but one that is FDA-approved to manufacture pharmaceuticals.

Organizations such as, in our opinion are really useless since they apparently test only one batch of a product before declaring it to be “acceptable.” This makes as much sense as determining the quality of the teaching at a school by picking one child at random and testing that child, and no others. Obviously, a larger number of tests must be performed to get a meaningful idea of the quality as a whole.


Report Your Experience With ASU Here

Be sure to include the brand of the ASU product you’re taking and the dose (how many milligrams or mg per day). Also list and any other supplements or drugs you typically use on a regular basis.

Check back to this section for updates or give us your e-mail and we’ll notify you as soon as specifics become available.


Where to Find ASU Products


AVOSOY? Products

(available in the US without prescription)


Learn about and purchase the book

90% of people who follow The Arthritis Cure treatment program don't need anti-inflammatories (like Aleve, Celebrex or Advil).
Dr. Theo warned people that these drugs, used first... read more



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