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Side
Effects of Glucosamine and Chondroitin
In
addition to the findings of NIH's
GAIT Study, Dr. Theo's experience with the public also
indicates a high interest in the positive effects of Glucosamine
and Chondroitin. From over a million visitors to our website
pages on these subjects and with an estimated 15,000 e-mails received,
only 107 reported negative side effects. Of course, these side effects may be due to something besides the supplements, but we track this information to look for trends. If a trend is noted, thiss is added to a clinical study to see if the finding was causative, or just due to chance. Based on national sales
figures, millions of people rely on glucosamine/chondroitin in the US and about 100 million people world-wide.
It should be noted that in every clinical study and review article, glucosamine/chondroitin and ASU have been associated with increased adverse effects compared to placebo.
Here
is a breakdown of those reporting side effects:
| #
of Cases |
Reported
Problem |
| 27 |
Indigestion |
| 18 |
Excessive
gas |
| 14 |
Elevated
cholesterol |
| 10 |
Constipation |
| 12 |
High
blood pressure (linked to a products with high sodium) |
| 10 |
Rash |
| 8 |
Headache |
| 5 |
Diarrhea
|
| 5 |
Itching |
| 3 |
Elevated
blood sugar |
| 2 |
Lowered
cholesterol |
| 1 |
Low
blood sugar |
1
1 |
Confusion
Funny smell (also occurs with Bextra) |
| 1 |
Improved
vision |
Note:
Just because someone reports a side
effect does not mean the supplement caused the problem. People
not taking any drug or supplements can experience these problems
and often do. The purpose of this anecdotal reporting is to monitor
and report any trends.
FDA Reported Side Effects
Below are side-effects reported to the FDA concerning
products containing glucosamine and/or chondroitin.
Note:
The side effects reported here may be due to substances other
than glucosamine and/or chondroitin, especially for those products
that have multiple active ingredients. Furthermore, the FDA's
reports are not designed to exclude coincidental side effects.
If someone trips and falls, did their glucosamine cause it?
| ARMS
Number |
Adverse
Event as Reported |
Name
of Product |
Manufacturer |
Ingredients |
9921
|
Hepatitis range levels of SGOT and PT in blood |
Arthritin |
VAXA International Inc |
DL-methionine, glucosamine sulfate, GLA, mucopolysaccharides,
perna canaliculus, boswellia serrata, DL-phenylalanine, chondroitin
sulfate, shark cartilage, willow, tanacetum parthenium, others |
11542
|
Chin laceration and broken ankle from falling |
Glucosamine Sulfate |
Now Foods |
glucosamine sulfate |
11922
|
Developed dermatomyositis |
Glucosamine |
Pacific Research Distributors |
coenzyme Q-10, glutathione reduced, ?, N-acetylcysteine,
pycnogenol, taurine, ?, vitamin B2, copper, zinc, manganese |
12410
|
Diffuse pulmonary hemorrhage |
Joint Fuel |
Twin Labs Inc |
glucosamine sulfate, chondroitin sulfate, chelated
zinc picolinate, chelated manganese gluconate, vitamin C, vitamin
E, selenium, turmeric extract, quercetin, bromelain |
12421
|
Pancreatitis |
Arthaffect with Arthred |
Reliv Inc |
arthred, glucosamine sulfate, ginkgo biloba, borage
oil, turmeric, boswellia serrata, ashwagandha, cat's claw, sarsaparilla
root, licorice root, burdock root, barley grass, echinacea, yucca,
devil's claw, bilberry, capsicum, aloe vera, bioperine, others |
12529
|
Developed nodule on wrist |
Glucosamine |
Windmill Consumer Products |
glucosamine |
12529
|
Developed nodule on wrist |
Chondroigen Sulfate (Chondroitin Sulfate?) |
Windmill Consumer Products |
chondroitin sulfate |
12707
|
Edema, difficulty breathing |
Glucoamine and Chondroitin |
Amerifit |
vitamin C, calcium, phosphorus, zinc, copper, glucosamine
hydrochloride, chondroitin sulfate, citrus bioflavonoids, microcrystalline
cellulose, croscarmellose sodium, vegetable stearic acid, vegetable
magnesium stearate, pharmaceutical glaze |
12718
|
Developed heart problems |
Glucosamine 500mg |
Basic |
glucosamine |
12718
|
Developed heart problems |
Chondroitin Sulfate 400mg |
Basic |
chondroitin sulfate |
For
more detailed information concerning this data, please visit FDA.gov
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Learn about and purchase the book90% of people who follow The Arthritis Cure treatment program don't need anti-inflammatories (like Aleve, Celebrex or Advil).
Dr. Theo warned people that these drugs, used first... read more
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